There are two ways to connect Instagram to Wazzup: Instagram API and Instagram Personal. Both allow you to direct mail and reply to comments.
Instagram API. The official connection from Instagram with no bans or blocking. Works like clockwork.
Instagram Personal. Archived Instagram personal account connection. It was used until Instagram released an official solution. Not very stable and the account can get banned.
Of course, you can connect Instagram Personal and add proxies, try to avoid a ban, suffer from occasional crashes. But you can go the easy way and connect the Instagram API for the same money. What we recommend to you.